Dexamethasone Recall

On March 16th, 2011,the FDA published on their website that  American Regent has recalled Dexamethasone Sodium Phosphate.  This recall was due to some of the vials containing particulates or having the potential to form particulates prior to their respective expiration dates.  It is believed this may disrupt blood flow within small blood vessels in the lung as well as cause localized inflammation and granuloma formation.  It is recommended that clinics using this should discontinue immediately to prevent liability issues.  To read more click here.


All Comments

  • Thank you for the article Joe! Has anyone switched to acetic acid for the treatment of plantar fasciitis? If so, what dosage do you find to be most effective?

    Aisling Linehan March 23, 2011 2:55 pm Reply
  • I use acetic acid for achilles tendonopathies in which there is a visible exocytosis or bony build-up/bump in the region of inserion into the calcaneous. I use a 4-5% solutions which has shown to be effective in diminishing the excess calcification in this region.

    joebrence9 March 23, 2011 3:43 pm Reply
    • Will the acetic acid work once the bone is calcified and hardened? I was under the impression that it could only work while the bone was in the fluffy callous phase…where the is still a precipitate of hydroxyapatite….which becomes soluble once the pH is lowered (by the acetic acid)

      John Duffy March 23, 2011 7:48 pm
  • Hey Duffy,
    I am under the impression that it may be effective once the bone is calcified and would like to refer you to: (if you want the full txt Ill send this to you)…The study indicated acetic acid was effective in decreasing pain in those with chronic heel pain (I am assuming, not positive, that the chronicity of the disorder likely led to calcification of some of the subjects tendons). Average pain in subjects treated with acetic acid decreased from 7.5 to 1.8. That stated, I havent seen replication of this and the outcomes were assessed by subjective pain results vs. calcification measurements (in my last response, I mistakenly said it was effective in diminishing this calcification and we only know that the subjects pain was reduced vs. calcification…had to go back to the article to refresh myself on the results)….I use acetic acid clinically for the treatment of achilles tendonitis and when combined with eccentric loading to the tendon, have gotten fairly good results…

    joebrence9 March 24, 2011 1:38 am Reply
  • Regarding the Dexamethasone recalled bottles. I am still suffering injuries caused by treatments I had with a recalled bottle of this drug. I would appreciate feedback from anyone else that has or still is suffering adverse side effects from the use of this drug. I have continuous swelling, sleeplessness, severe pain from this drug. I have seen several doctors and specialists with no relief. I have reported my adverse effects to the FDA and encourage anyone else that has been hurt by Dexamethasone to please report it to the FDA right away. I am looking for information because the company American Regent and Luitpold Pharmacuticals will not help me to remedy my injuries. My doctors said they will not call these people for fear anything they would tell them they will use against me if a lawsuit should come about. At this point I want to feel well again and it has been almost a year since this happened to me. I’m still suffering terribly. You can also email me at

    Lori October 26, 2011 2:33 am Reply

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